Pittsburgh Center for Evolutionary Biology and Medicine (CEBaM)
The mission of the Center is to advance the fields of evolutionary biology and medicine by catalyzing research at their interface. The Center serves to cultivate educational and scientific collaborations between evolutionary biologists and biomedical researchers.
News & Events
CEBaM Lecture Series: 2023-2024 Dates
Please join the Center for Evolutionary Biology and Medicine for our 2023-2024 Lecture Series! Noon…
2023 Catalyst Award Recipients Announced
Please join us in congratulating the 2023 Catalyst Award Recipients! Jiwon LeeJiwon is a Ph.D….
2023 George C. Williams Prize Awarded to Cooper & Collaborators
Congratulations to CEMaM’s own Vaughn Cooper and collaborators Alfonso Santos-Lopez, Melissa J Fritz, Jeffrey B Lombardo, Ansen H…
Recent Publications
Haidar, G., Chan, B. K., Cho, S. T., Hughes Kramer, K., Nordstrom, H. R., Wallace, N. R., Stellfox, M. E., Holland, M., Kline, E. G., Kozar, J. M., Kilaru, S. D., Pilewski, J. M., LiPuma, J. J., Cooper, V. S., Shields, R. K., & Van Tyne, D. (2023). Phage therapy in a lung transplant recipient with cystic fibrosis infected with multidrug-resistant Burkholderia multivorans. Transplant infectious disease : an official journal of the Transplantation Society, 25(2), e14041.
Muraski, M. J., Nilsson, E. M., Fritz, M. J., Richardson, A. R., Alexander, R. W., & Cooper, V. S. (2023). Adaptation to Overflow Metabolism by Mutations That Impair tRNA Modification in Experimentally Evolved Bacteria. mBio, 14(2), e0028723.
Balcı, A. T., Ebeid, M. M., Benos, P. V., Kostka, D., & Chikina, M. (2023). An intrinsically interpretable neural network architecture for sequence to function learning. bioRxiv : the preprint server for biology, 2023.01.25.525572.
Schriever, H., & Kostka, D. (2023). Vaeda computationally annotates doublets in single-cell RNA sequencing data. Bioinformatics (Oxford, England), 39(1), btac720.
Rich A*, Acar O*, Carvunis AR.* (2023) Massively integrated coexpression analysis reveals transcriptional regulation, evolution and cellular implications of the noncanonical translatome. bioRxiv.
Wacholder A, Parikh SB, Coelho NC, Acar O, Houghton C, Chou L, Carvunis AR. (2023). A vast evolutionarily transient translatome contributes to phenotype and fitness. Cell Systems, 14(5), P363-381.
Wacholder A & Carvunis AR. (2023). Rare detection of noncanonical proteins in yeast mass spectrometry studies. bioRxiv.
Evans, D., Sundermann, A., Griffith, M., Rangachar Srinivasa, V., Mustapha, M., Chen, J., Dubrawski, A., Cooper, V., Harrison, L., & Van Tyne, D. (2023). Empirically derived sequence similarity thresholds to study the genomic epidemiology of plasmids shared among healthcare-associated bacterial pathogens. EBioMedicine, 93, 104681.
Srinivasa, V. R., Griffith, M. P., Waggle, K. D., Johnson, M., Zhu, L., Williams, J. V., Marsh, J. W., Van Tyne, D., Harrison, L. H., & Martin, E. M. (2023). Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Among University Students in Western Pennsylvania. The Journal of infectious diseases, 228(1), 37–45.
Haidar, G., Chan, B. K., Cho, S. T., Hughes Kramer, K., Nordstrom, H. R., Wallace, N. R., Stellfox, M. E., Holland, M., Kline, E. G., Kozar, J. M., Kilaru, S. D., Pilewski, J. M., LiPuma, J. J., Cooper, V. S., Shields, R. K., & Van Tyne, D. (2023). Phage therapy in a lung transplant recipient with cystic fibrosis infected with multidrug-resistant Burkholderia multivorans. Transplant infectious disease : an official journal of the Transplantation Society, 25(2), e14041.
Rich A, Carvunis AR. (2023) De nova gene increases brain size. Nature Ecology & Evolution.
Club EvMed is a web series launched in April 2020 to keep the evolutionary medicine community connected during a time of pandemic-related social distancing. These regularly-held virtual meetings are styled around the idea of a journal club, with a different topic and discussion leader each time.